Homoklorsiklizin

Homoklorsiklizin
Nama sistematis (IUPAC)
	1-[(4-klorofenil)-fenilmetil]-4-metil-1,4-diazepana
Data klinis
AHFS/Drugs.com	International Drug Names
Kat. kehamilan	?
Status hukum	℞ Preskripsi saja
Rute	Oral
Pengenal
Nomor CAS	848-53-3
Kode ATC	None
PubChem	CID 3627
ChemSpider	3501
UNII	N5MVC31W2N
KEGG	D08041
ChEMBL	CHEMBL151447
Data kimia
Rumus	C19H23ClN2
SMILES	eMolecules & PubChem

Homoklorsiklizin (INN) adalah antihistamin golongan difenilmetilpiperazin yang telah dipasarkan di Jepang sejak tahun 1965.^[1] Obat ini digunakan dalam pengobatan alergi dan kondisi lainnya. Obat ini juga memiliki beberapa sifat antikolinergik, antidopaminergik, dan antiserotonergik.^[2]^[3]

Referensi

^ "Homoclomin Tablets 10 mg" (PDF). Eisai Co. December 2007. Diakses tanggal 2008-07-29. ^{[pranala nonaktif]}
^ Haraguchi K, Ito K, Kotaki H, Sawada Y, Iga T (June 1997). "Prediction of drug-induced catalepsy based on dopamine D1, D2, and muscarinic acetylcholine receptor occupancies". Drug Metabolism and Disposition. 25 (6): 675–84. PMID 9193868.
^ KIMURA ET, YOUNG PR, RICHARDS RK (1960). "Pharmacologic properties of N-p-chloro-benzhydryl-N'-methyl homopiperazine dihydrochloride (homochlorcyclizine; SA-97), a serotonin antagonist". Journal of Allergy. 31: 237–47. doi:10.1016/0021-8707(60)90052-6. PMID 14409112.

[1] "Homoclomin Tablets 10 mg" (PDF). Eisai Co. December 2007. Diakses tanggal 2008-07-29. ^{[pranala nonaktif]}

[pmid9193868-2] Haraguchi K, Ito K, Kotaki H, Sawada Y, Iga T (June 1997). "Prediction of drug-induced catalepsy based on dopamine D1, D2, and muscarinic acetylcholine receptor occupancies". Drug Metabolism and Disposition. 25 (6): 675–84. PMID 9193868.

[pmid14409112-3] KIMURA ET, YOUNG PR, RICHARDS RK (1960). "Pharmacologic properties of N-p-chloro-benzhydryl-N'-methyl homopiperazine dihydrochloride (homochlorcyclizine; SA-97), a serotonin antagonist". Journal of Allergy. 31: 237–47. doi:10.1016/0021-8707(60)90052-6. PMID 14409112.

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