IFNA14

Interferon, alpha 14
Tanda pengenal
Simbol	IFNA14; IFN-alphaH; LEIF2H
ID eksternal	OMIM: 147579 HomoloGene: 122139 GeneCards: IFNA14 Gene
Gene Ontology
Fungsi molekul	• cytokine activity; • cytokine receptor binding;
Komponen sel	• extracellular region; • extracellular space;
Proses biologis	• blood coagulation; • cytokine-mediated signaling pathway; • innate immune response; • defense response to virus; • type I interferon-mediated signaling pathway; • regulation of type I interferon-mediated signaling pathway;
	Sumber: Amigo / QuickGO
Orthologs
	l; b; s;

IFNA14
Pengidentifikasi
Alias	IFNA14, IFN-alphaH, LEIF2H, interferon alpha 14
ID eksternal	OMIM: 147579 MGI: 2667155 HomoloGene: 122139 GeneCards: IFNA14
Ontologi gen
Fungsi molekuler	• cytokine activity; • type I interferon receptor binding; • GO:0005145 cytokine receptor binding;
Komponen seluler	• extracellular region; • extracellular space;
Proses biologis	• natural killer cell activation involved in immune response; • B cell differentiation; • defense response; • B cell proliferation; • Koagulasi; • positive regulation of peptidyl-serine phosphorylation of STAT protein; • humoral immune response; • adaptive immune response; • defense response to virus; • type I interferon signaling pathway; • response to exogenous dsRNA; • T cell activation involved in immune response; • Sistem kekebalan turunan; • cytokine-mediated signaling pathway; • regulation of signaling receptor activity;
	Sumber:Amigo / QuickGO
Ortolog
	3448
	230396
	ENSG00000228083
	ENSMUSG00000063376
	P01570
	Q80SU4
	NM_002172
	NM_177347
	NP_002163
	NP_796321
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

Interferon alpha-14 adalah protein yang pada manusia disandikan oleh gen IFNA14.^[3]^[4]

Referensi

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.
^ "Entrez Gene: IFNA14 interferon, alpha 14".

Bacaan lanjutan

Sen GC, Lengyel P (1992). "The interferon system. A bird's eye view of its biochemistry". J. Biol. Chem. 267 (8): 5017–20. PMID 1371992.
Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151.
Henco K, Brosius J, Fujisawa A; et al. (1985). "Structural relationship of human interferon alpha genes and pseudogenes". J. Mol. Biol. 185 (2): 227–60. doi:10.1016/0022-2836(85)90401-2. PMID 4057246.
Goeddel DV, Leung DW, Dull TJ; et al. (1981). "The structure of eight distinct cloned human leukocyte interferon cDNAs". Nature. 290 (5801): 20–6. doi:10.1038/290020a0. PMID 6163083.
Lawn RM, Adelman J, Dull TJ; et al. (1981). "DNA sequence of two closely linked human leukocyte interferon genes". Science. 212 (4499): 1159–62. doi:10.1126/science.6165082. PMID 6165082.
Tiefenbrun N, Melamed D, Levy N; et al. (1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. 16 (7): 3934–44. PMC 231390 . PMID 8668211.
Hussain M, Gill DS, Liao MJ (1997). "Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a large human population". J. Interferon Cytokine Res. 16 (10): 853–9. doi:10.1089/jir.1996.16.853. PMID 8910771.
Nyman TA, Tölö H, Parkkinen J, Kalkkinen N (1998). "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes". Biochem. J. 329 ( Pt 2) (Pt 2): 295–302. PMC 1219044 . PMID 9425112.
Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 . PMID 12477932.
Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.

Artikel bertopik protein ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya.

[1] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[2] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1385305-3] Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.

[entrez-4] "Entrez Gene: IFNA14 interferon, alpha 14".

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